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Poliomyelitis
Definition
Poliomyelitis is a viral disease that can affect nerves and can lead to partial or full paralysis.
Alternative Names
Polio; Infantile paralysis; Post-polio syndrome
Causes
Poliomyelitis is a disease caused by infection with the poliovirus. The virus spreads by:
- Direct person-to-person contact
- Contact with infected mucus or phlegm from the nose or mouth
- Contact with infected feces
The virus enters through the mouth and nose, multiplies in the throat and intestinal tract, and then is absorbed and spread through the blood and lymph system. The time from being infected with the virus to developing symptoms of disease (incubation) ranges from 5 - 35 days (average 7 - 14 days). Most people do not develop symptoms.
Risks include:
- Lack of immunization against polio
- Travel to an area that has experienced a polio outbreak
Outbreaks can still occur in the developed world, usually in groups of people who have not been vaccinated. Polio often occurs after someone travels to a region where the disease is common. As a result of a massive, global vaccination campaign over the past 20 years, polio exists only in a few countries in Africa and Asia.
Symptoms
There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Most people have subclinical infection, and may not have symptoms.
SUBCLINICAL INFECTION SYMPTOMS
People with subclinical polio infection might not have symptoms, or mild symptoms may last 72 hours or less.
Clinical poliomyelitis affects the central nervous system (brain and spinal cord), and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection.
Exams and Tests
The health care provider may find:
- Abnormal reflexes
- Back stiffness
- Difficulty lifting the head or legs when lying flat on the back
- Stiff neck
- Trouble bending the neck
Tests include:
- Cultures of throat washings, stools, or spinal fluid
- Spinal tap and examination of the spinal fluid (CSF examination )
- Test for levels of antibodies to the polio virus
Treatment
The goal of treatment is to control symptoms while the infection runs its course.
People with severe cases may need lifesaving measures, especially breathing help.
Symptoms are treated based on their severity. Treatment may include:
- Antibiotics for urinary tract infections
- Moist heat (heating pads, warm towels) to reduce muscle pain and spasms
- Painkillers to reduce headache, muscle pain, and spasms (narcotics are not usually given because they increase the risk of breathing trouble)
- Physical therapy, braces or corrective shoes, or orthopedic surgery to help recover muscle strength and function
Outlook (Prognosis)
The outlook depends on the form of the disease (subclinical, or paralytic) and the body area affected. Most of the time, complete recovery is likely if the spinal cord and brain are not involved.
Brain or spinal cord involvement is a medical emergency that may result in paralysis or death (usually from respiratory problems).
Disability is more common than death. Infection that is located high in the spinal cord or in the brain increases the risk of breathing problems.
Possible Complications
- Aspiration pneumonia
- Cor pulmonale (a form of heart failure found on the right side of the circulation system)
- Lack of movement
- Lung problems
- Myocarditis
- Paralytic ileus (loss of intestinal function)
- Permanent muscle paralysis, disability, deformity
- Pulmonary edema
- Shock
- Urinary tract infections
Post-polio syndrome is a complication that develops in some patients, usually 30 or more years after they are first infected. Muscles that were already weak may get weaker. Weakness may also develop in muscles that were not affected before.
When to Contact a Medical Professional
Call your health care provider if:
- Someone close to you has developed poliomyelitis and you haven't been vaccinated
- You develop symptoms of poliomyelitis
- Your child's polio immunization (vaccine) is not up to date
Prevention
Polio immunization (vaccine) effectively prevents poliomyelitis in most people (immunization is over 90% effective).
References
Modlin JF. Poliovirus. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2009:chap 171.
Silver JK. Post-poliomyelitis syndrome. In: Frontera WR, Silver JK, Rizzo Jr TD, eds. Essentials of Physical Medicine and Rehabilitation. 2nd ed. Philadelphia, Pa: Saunders Elsevier; 2008: chap 137.
Reviewed By: David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc. Linda J. Vorvick, MD, Medical Director and Director of Didactic Curriculum, MEDEX Northwest Division of Physician Assistant Studies, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital.
