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Antiparietal cells antibodies test
Definition
An antiparietal cells antibodies test is a blood test that looks for antibodies against the parietal cells of the stomach. The parietal cells make and release a substance that the body needs to absorb vitamin B12.
Alternative Names
APCA; Anti-gastric parietal cell antibodies
How the Test is Performed
A blood sample is needed. For information on how this is done, see:
How to Prepare for the Test
No special preparation is necessary.
Why the Test is Performed
Your health care provider may use this test to help diagnose pernicious anemia. Other tests are also used to help with the diagnosis.
Normal Results
A negative result is normal.
What Abnormal Results Mean
A positive test result is abnormal. This may be due to:
- Atrophic gastritis
- Diabetes
- Gastric ulcer
- Pernicious anemia
- Thyroid disease
Risks
Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
References
Antony AC. Megaloblastic anemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 170.
Reviewed By: Todd Eisner, MD, Private practice specializing in Gastroenterology, Boca Raton, FL. Olinical Instructor, Florida Atlantic University School of Medicine. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
